Fecal Myeloperoxidase Levels in Pregnant Women and Risk Factors to Low Birth Weight in A Makassar Slum Settlement: A Sub-Study of The Indonesian Birth Cohort Study
Fecal Myeloperoxidase Levels in Pregnant Women and Risk Factors to Low Birth Weight in A Makassar Slum Settlement: A Sub-Study of The Indonesian Birth Cohort Study
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Purpose: Intestinal inflammation can affect the absorption of micronutrients from the bowel, which can lead to maternal malnutrition and adverse pregnancy outcomes.This study aimed to measure fecal myeloperoxidase (MPO) levels as a biomarker of inflammation in pregnant women and explore risk factors for low birth weight in the slum area of the Tallo District, Makassar City.Method: This study used a retrospective cohort study design with a purposive sample of 172 pregnant women.
Stool specimens were collected and tested using a human myeloperoxidase enzyme-linked immunosorbent assay kit.Data were collected through interviews using the Kobo Toolbox.Result: The median lorenametaute.com fecal myeloperoxidase level in pregnant women was 24.
2 ng/ml.The correlation with low birth weight was insignificant (r = -0.0037, p = 0.
96).Based on bivariate analysis, the risk factors significantly associated with low birth weight were first parity (RR = 2.8 (95% CI: 1.
3-6.4), and preterm birth (RR = 3.9 (95% CI: 1.
9-8.3), while the dodge warlord for sale multivariate analysis showed that the most significant risk variable for low birth weight was preterm birth (ARR = 4.9 (95% CI: 2.
6-9.1).Conclusion: This study found that gestational age at birth was significantly associated with low birth weight in infants.
There was no significant association with fecal myeloperoxidase level in the pregnant mother.